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Test ID NBLD0523 14-3-3 Protein, CSF (Prion Disease)

Specimen Type/Requirements

Sterile Container - CSF

 

Collect CSF by lumbar puncture.  Discard first 2 mL that flows from tap.  Collect next 5 mL CSF, avoiding a bloody tap.  Freeze within 20 minutes of collection.  Store and transport frozen.  Ship using styrofoam container with sufficient dry ice (5 lbs/24 hours).  The National Prion Disease Pathology Surveillance Center requests a urine sample for research purposes with all CSF samples if available.  

 

Test is affected by hemolysis.  Test is not affected by lipemia.

Stability/Transport

 Room Temperature     24 hours     
 Refrigerated     14 days     
 Frozen     Indefinitely     Preferred for transport   

 

Methodology

Immunoassay, RT-QuIC

Performing Lab

Quest Chantilly forwards to National Prion Disease Pathology Surveillance Center

CPT

0035U, 83520

Specimen Volume

 Preferred Volume     5 mL CSF   
 Minimum Volume     2 mL CSF   

 

Report Available

21 days

Performed Test Frequency

Tuesday and Thursday

Interface Build Information

SANFORD LABORATORY INTERFACE BUILD INFORMATION

 Result Code     Result Code Description   
 25998  Likelihood of Prion Disease   
 25999  RT-QuIC (CSF)*
 26000  T-tau Protein (CSF)++
 26001  14-3-3 GAMMA (CSF)++
 25092  Comment