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Test ID DULOX Duloxetine, Serum

Reporting Name

Duloxetine, S

Useful For

Monitoring serum concentration during therapy 


Evaluating potential toxicity 


Evaluating patient compliance

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red

Specimen Required

Container/Tube: Red top

Specimen Volume: 1 mL

Collection Instructions: 

1. As is the case for most therapeutic drugs, trough specimens are preferred for monitoring duloxetine concentrations and should be drawn immediately before the next scheduled dose.

2. Spin down within 2 hours of draw.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  24 hours

Reference Values

60-120 ng/mL

Day(s) and Time(s) Performed

Tuesday; 4 p.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


Reject Due To


Mild OK; Gross OK


Mild OK; Gross OK


Mild OK; Gross OK


Serum gel tube


Method Name

High-Turbulence Liquid Chromatography Mass Spectrometry (HTLC-MS/MS)