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Test ID BLOD5035 Streptococcus pneumoniae IgG Antibodies, 23 Serotypes, Serum


Ordering Guidance


This test is the preferred test for patients previously tested for Streptococcus pneumoniae serotypes (as part of follow up testing or part of pre/post vaccine assessment).

 

The preferred test for patients being evaluated for possible immunodeficiency or for assessment of pneumococcal vaccination response (initial evaluation) is PNTOR / Streptococcus pneumoniae IgG Antibodies, Total, with Reflex, Serum

 

The preferred test for patients previously tested for total Streptococcus pneumoniae antibodies (as part of follow up testing or part of pre/post vaccine assessment) is PNTO / Streptococcus pneumoniae IgG Antibodies, Total, Serum



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial 

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial


Secondary ID

619921

Useful For

Assessing the IgG antibody response to active immunization with nonconjugated, 23-valent pneumococcal vaccines

 

Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal vaccines

 

Determining the ability of an individual to produce an antibody response to polysaccharide antigens, as part of the evaluation for humoral or combined immunodeficiencies

Method Name

Bead-Based Multiplex Immunoassay

Reporting Name

S. pneumoniae IgG Ab,23 serotypes,S

Specimen Type

Serum

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

Results are reported in mcg/mL

 

Serotype

Normal value

1 (1)

≥1.0

2 (2)

≥1.0

3 (3)

≥1.0

4 (4)

≥1.0

5 (5)

≥1.0

8 (8)

≥1.0

9N (9)

≥1.0

12F (12)

≥1.0

14 (14)

≥1.0

17F (17)

≥1.0

19F (19)

≥1.0

20 (20)

≥1.0

22F (22)

≥1.0

23F (23)

≥1.0

6B (26)

≥1.0

10A (34)

≥1.0

11A (43)

≥1.0

7F (51)

≥1.0

15B (54)

≥1.0

18C (56)

≥1.0

19A (57)

≥1.0

9V (68)

≥1.0

33F (70)

≥1.0

Day(s) Performed

Monday through Friday

Report Available

4 to 6 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86317 x 23

Forms

If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.

Sanford Laboratories - Bismarck Additional Information:

SANFORD LABORATORY INTERFACE BUILD INFORMATION

 Result Code     Result Code Description   
 17674  Serotype 1 (1)
 17675  Serotype 2 (2)
 17676  Serotype 3 (3)
 17677  Serotype 4 (4)
 17678  Serotype 5 (5)
 17679  Serotype 8 (8)
 17680   Serotype 9N (9)
 17681  Serotype 12F (17)
 17682  Serotype 14 (14)
 17683  Serotype 17F (17)
 17684  Serotype 19F (19)
 17685  Serotype 20 (20)
 17686  Serotype 22F (23)
 17687  Serotype 23F (23)
 17688  Serotype 6B (26)
 17689  Serotype 10A (34)
 17690  Serotype 11A (43)
 17691  Serotype 7F (51)
 17692  Serotype 15B (54)
 17693  Serotype 18C (56)
 17694  Serotype 19A (57)
 17695  Serotype 9V (68)
 17696  Serotype 33F (70)
 25703  Interpretation