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Test ID BLOD1303 Ganglioside Antibodies Evaluation, Serum


Specimen Required


Patient Preparation: For optimal antibody detection, specimen collection is recommended to occur prior to initiation of immunosuppressant medication or intravenous immunoglobulin treatment.

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Secondary ID

621108

Useful For

Supporting the diagnosis of an autoimmune neuropathy

Profile Information

Test ID Reporting Name Available Separately Always Performed
GAESI Ganglioside Antibodies Interp, S No Yes
GQ1ES GQ1b-IgG ELISA, S Yes Yes
IGG_D IgG Disialo. GD1b No Yes
IGM_D IgM Disialo. GD1b No Yes
IGG_M IgG Monos. GM1 No Yes
IGM_M IgM Monos. GM1 No Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
IGDTS IgG Disialo GD1b Titer, S No No
IMDTS IgM Disialo GD1b Titer, S No No
IGMTS IgG Monos GM1 Titer, S No No
IMMTS IgM Monos GM1 Titer, S No No

Testing Algorithm

Screening tests are performed for IgG and IgM antibodies to gangliosides GM1 and GD1b. If positive, the appropriate titer will be performed at an additional charge.

 

For more information see:

-Ganglioside Antibody Panel Algorithm.

-Acquired Neuropathy Diagnostic Algorithm

Method Name

GQ1ES, IGG_D, IGM_D, IGG_M, IGM_M, IGDTS, IMDTS, IGMTS, IMMTS: Enzyme-Linked Immunosorbent Assay (ELISA)

GAESI: Technical Interpretation

Reporting Name

Ganglioside Antibodies Eval, S

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

GQ1b-IgG ELISA: Negative

IgG Disialo. GD1b: Negative

IgM Disialo. GD1b: Negative

IgG Monos. GM1: Negative

IgM Monos. GM1: Negative

 

IgG Disialo GD1b Titer: <1:2000

IgM Disialo GD1b Titer: <1:2000

IgG Monos GM1 Titer: <1:2000

IgM Monos GM1 Titer: <1:4000

Day(s) Performed

Monday, Wednesday, Friday

Report Available

5 to 8 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83516 x5

83520 x4 (if applicable)