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Test ID NBLD0542 Drugs of Abuse Screen 5, Chain of Custody, Meconium

Useful For

Identifying amphetamines (and methamphetamines), opiates, as well as metabolites of cocaine and marijuana in meconium specimens

               

Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by demonstrating that it was under the control of personnel involved with testing the specimen at all times; this control implies that the opportunity for specimen tampering would be limited. Since the evidence of illicit drug use during pregnancy can be cause for separating the baby from the mother, a complete chain of custody ensures that the test results are appropriate for legal proceedings.

Additional Tests

Test ID Reporting Name Available Separately Always Performed
COCH Chain of Custody Processing No Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
COKMX Cocaine and metabolite Conf, CoC, M Yes No
OPTMX Opiate Confirmation, CoC, M Yes No
PCPMX Phencyclidine Confirmation, CoC, M Yes No
THCMX Carboxy-THC Confirmation, CoC, M Yes No
AMPMX Amphetamines Confirmation, CoC, M Yes No

Testing Algorithm

Testing begins with immunoassay screen. Positives are confirmed and quantitated by liquid chromatography-tandem mass spectrometry (LC-MS/MS) at an additional charge.

Reporting Name

Drugs of Abuse Screen 5, CoC, M

Specimen Type

Meconium


Specimen Required


Container/Tube: Chain-of-Custody Meconium Kit (T653) includes the specimen containers, seals, and documentation required

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions: Collect entire random meconium specimen.

Additional Information:

1. Specimen that arrives with a broken seal does not meet the chain-of-custody requirements.

2. The laboratory recommends sending chain-of-custody specimens by overnight shipment.


Specimen Minimum Volume

0.45 g (approximately 0.5 teaspoon)

Specimen Stability Information

Specimen Type Temperature Time
Meconium Frozen (preferred) 14 days
  Refrigerated  24 hours

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

Grossly bloody reject; Pink OK

Reference Values

Negative

Positives are reported with a quantitative LC-MS/MS result.

Cutoff concentrations       

Amphetamines by ELISA: 100 ng/g

Methamphetamine by ELISA: 100 ng/g

Benzoylecgonine (cocaine metabolite) by ELISA: 100 ng/g

Opiates by ELISA: 100 ng/g

Tetrahydrocannabinol carboxylic acid (marijuana metabolite) by ELISA: 20 ng/g

Phencyclidine by ELISA: 20 ng/g

Day(s) and Time(s) Performed

Monday through Saturday

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80307

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DSM5X Drugs of Abuse Screen 5, CoC, M In Process

 

Result ID Test Result Name Result LOINC Value
36178 Amphetamine 26959-7
36179 Methamphetamine 27289-8
36180 Cocaine 26956-3
36181 Opiate 29158-3
36182 Phencyclidine 26859-9
36183 Tetrahydrocannabinol 26893-8
36184 Chain of Custody No LOINC Needed

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)