Sign in →

Test ID BLOD0397 Carbamazepine-10,11-Epoxide, Serum

Useful For

Monitoring patients exhibiting symptoms of carbamazepine toxicity whose serum carbamazepine concentration is within the therapeutic range, but who may be producing significant levels of the active metabolite epoxide

Profile Information

Test ID Reporting Name Available Separately Always Performed
CARTA Carbamazepine, Tot, S Yes Yes
1011E Carb-10,11-Epoxide, S No Yes

Method Name

CARTA: Immunoassay         
1011E: High-Performance Liquid Chromatography (HPLC)

Reporting Name

Carbamazepine-10,11-Epoxide, S

Specimen Type

Serum Red

Specimen Required

Container/Tube: Red top
Specimen Volume: 2 mL
Collection Instructions: Draw blood 12 hours (trough value) after last dose.

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 14 days
  Ambient  14 days
  Frozen  14 days

Reject Due To


Mild OK; Gross reject


Mild OK; Gross reject


Mild OK; Gross reject


Whole blood, plasma, or serum gel tube

Reference Values

Therapeutic: 4.0-12.0 mcg/mL
Critical value: >  or =15.0 mcg/mL


Therapeutic concentration: 0.4-4.0 mcg/mL
Toxic concentration: ≥8.0 mcg/mL

Day(s) and Time(s) Performed

CARTA: Monday through Sunday; Continuously
1011E: Wednesday; 11 a.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80156-Carbamazepine, total


LOINC Code Information

Test ID Test Order Name Order LOINC Value
CARBG Carbamazepine-10,11-Epoxide, S In Process


Result ID Test Result Name Result LOINC Value
7467 Carb-10,11-Epoxide, S 9415-1
CARTA Carbamazepine, Tot, S 3432-2