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Test ID BLOD0206 Serotonin, Serum

Reporting Name

Serotonin, S

Useful For

In conjunction with, or as an alternative to first-order test in the differential diagnosis of isolated symptoms suggestive of carcinoid syndrome, in particular flushing (5-HIAA or serum chromogranin A measurements are first-line tests)

 

Second-order test in the follow-up of patients with known or treated carcinoid tumors in serum specimens

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Collection Container/Tube: 

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 2.5 mL

Collection Instructions: Spin down as soon as blood has clotted.

Additional Information: Medications that may affect serotonin concentrations include lithium, monoamine oxidase inhibitors, methyldopa, morphine, and reserpine.


Specimen Minimum Volume

1.1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 90 days
  Refrigerated  24 hours

Reference Values

≤230 ng/mL

Day(s) and Time(s) Performed

Monday, Wednesday, Friday; 10 a.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

84260

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SER Serotonin, S 27057-9

 

Result ID Test Result Name Result LOINC Value
84395 Serotonin, S 27057-9

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

Mild OK; Gross OK

Icterus

Mild OK; Gross OK

Other

NA

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)